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recombinant human tgf β1  (MedChemExpress)


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    Structured Review

    MedChemExpress recombinant human tgf β1
    Recombinant Human Tgf β1, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 95/100, based on 16 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/recombinant+human+tgf+%CE%B21/TGF+beta+1%2FTGFB1%2C+Human/pm42887830-60-28-32
    Average 95 stars, based on 16 article reviews
    recombinant human tgf β1 - by Bioz Stars, 2026-11
    95/100 stars

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    Related Articles

    Recombinant:

    Article Title: Diverse roles of SERPINE1 in regulating cellular proliferation and invasion
    Article Snippet: The expression of 89 human cell cycle-related proteins was assessed using a label-based antibody array (cat. no. AAH-BLG-CYC-4, RayBiotech, Inc.) according to the manufacturer's protocol. .. The cells were treated with 0.5 ng/ml recombinant human TGF-β1 (cat. no. HY- P70543 ; MedChemExpress) or vehicle (4 mM HCl supplemented with 0.1% BSA) for 24 h to determine how exogenous TGF-β1 alters the expression of cell cycle-related proteins in C918-shSE1 cells, with three replicates per group. .. The cells were treated with 0.5 ng/ml recombinant human TGF-β1 (cat. no. HY- P70543 ; MedChemExpress) or vehicle (4 mM HCl supplemented with 0.1% BSA) for 24 h to determine how exogenous TGF-β1 alters the expression of cell cycle-related proteins in C918-shSE1 cells, with three replicates per group.

    Article Title: Wenyang Xiaozheng Decoction attenuates renal fibrosis and suppresses pyroptosis-associated signaling: insights from integrated transcriptomics and serum pharmacochemistry.
    Article Snippet: Ethnopharmacological relevance: Wenyang Xiaozheng Decoction (WXD) is traditionally prescribed for chronic kidney disease based on the principle of warming yang and resolving blood stasis.. However, whether its antifibrotic effects involve inflammation-associated pyroptosis remains unclear.. Aim of the study: To evaluate the effects of WXD on renal fibrosis and associated changes in NF-κBand pyroptosis-related signaling.

    Article Title: Proof-of-Concept Evaluation of Primary Human FAP-CAR-NK Cells Targeting Activated Fibroblasts in Pulmonary Fibrosis.
    Article Snippet: .. Recombinant human TGF-β1 (MedChemExpress (MCE), Monmouth Junction, NJ, USA, #HY-P7118, expressed in CHO cells) was reconstituted according to the manufacturer’s protocol. ..

    Article Title: PREX1 regulates renal fibrosis through the RPTOR-mTORC1 signaling pathway.
    Article Snippet: .. Prior to treatments, cells were synchronized by serum starvation for 12 h. To establish an in vitro model of renal fibrosis, cells were stimulated with 10 ng/mL of recombinant human TGF-β1 (MedChemExpress, Cat# HY-P7117) for 24 h. For loss-of-function studies, gene silencing was achieved by transfecting cells with 50 nM of either siPREX1 or siRPTOR using Lipofectamine 2000 (Invitrogen). ..

    Article Title: Acetylshikonin alleviates pulmonary fibrosis through inhibition of the STAT3 signaling pathway.
    Article Snippet: Pulmonary fibrosis (PF) is a refractory lung disease characterized by excessive extracellular matrix (ECM) deposition accompanied by inflammatory injury.. Acetylshikonin (ASH), a naphthoquinone derivative primarily sourced from the root of Lithospermum erythrorhizon, possesses a diverse array of biological properties, including antitumor and anti-inflammatory activities, yet its potential in mitigating PF remains unexplored.. We found that ASH ameliorated bleomycin-induced lung dysfunction and reduced lung inflammation levels, collagen deposition and Epithelial-mesenchymal transition (EMT) in mice.

    Article Title: Nrf2 overexpression attenuates TGF-β-induced EMT-like changes and ferroptosis-related stress in lung epithelial cells.
    Article Snippet: Objective: Transforming growth factor-β (TGF-β) is a key mediator of epithelial responses associated with pulmonary fibrotic remodeling.. This study examined how nuclear factor erythroid 2-related factor 2 (Nrf2) manipulation affects EMT-like responses and ferroptosis-related stress in TGF-β-treated lung epithelial cells.. Methods: A549 and BEAS-2B cells were treated with TGF-β.

    Article Title: INHBE is upregulated in MASLD and MASLD-related HCC and promotes lipid accumulation and malignant phenotypes in vitro
    Article Snippet: .. Lipid-loaded Huh7 cells with INHBE knockdown were treated with recombinant human TGF‐β1 (MCE, New Jersey, USA) to pharmacologically activate the SMAD signaling pathway. ..

    Article Title: Diverse roles of SERPINE1 in regulating cellular proliferation and invasion.
    Article Snippet: .. The cells were treated with 0.5 ng/ml recombinant human TGF‐β1 (cat. no. HY‐P70543; MedChemExpress) or vehicle (4 mM HCl supplemented with 0.1% BSA) for 24 h to determine how exogenous TGF‐β1 alters the expression of cell cycle‐related proteins in C918‐shSE1 cells, with three replicates per group. ..

    Expressing:

    Article Title: Diverse roles of SERPINE1 in regulating cellular proliferation and invasion
    Article Snippet: The expression of 89 human cell cycle-related proteins was assessed using a label-based antibody array (cat. no. AAH-BLG-CYC-4, RayBiotech, Inc.) according to the manufacturer's protocol. .. The cells were treated with 0.5 ng/ml recombinant human TGF-β1 (cat. no. HY- P70543 ; MedChemExpress) or vehicle (4 mM HCl supplemented with 0.1% BSA) for 24 h to determine how exogenous TGF-β1 alters the expression of cell cycle-related proteins in C918-shSE1 cells, with three replicates per group. .. The cells were treated with 0.5 ng/ml recombinant human TGF-β1 (cat. no. HY- P70543 ; MedChemExpress) or vehicle (4 mM HCl supplemented with 0.1% BSA) for 24 h to determine how exogenous TGF-β1 alters the expression of cell cycle-related proteins in C918-shSE1 cells, with three replicates per group.

    Article Title: Diverse roles of SERPINE1 in regulating cellular proliferation and invasion.
    Article Snippet: .. The cells were treated with 0.5 ng/ml recombinant human TGF‐β1 (cat. no. HY‐P70543; MedChemExpress) or vehicle (4 mM HCl supplemented with 0.1% BSA) for 24 h to determine how exogenous TGF‐β1 alters the expression of cell cycle‐related proteins in C918‐shSE1 cells, with three replicates per group. ..

    Capsules:

    Article Title: Wenyang Xiaozheng Decoction attenuates renal fibrosis and suppresses pyroptosis-associated signaling: insights from integrated transcriptomics and serum pharmacochemistry.
    Article Snippet: Ethnopharmacological relevance: Wenyang Xiaozheng Decoction (WXD) is traditionally prescribed for chronic kidney disease based on the principle of warming yang and resolving blood stasis.. However, whether its antifibrotic effects involve inflammation-associated pyroptosis remains unclear.. Aim of the study: To evaluate the effects of WXD on renal fibrosis and associated changes in NF-κBand pyroptosis-related signaling.

    In Vitro:

    Article Title: PREX1 regulates renal fibrosis through the RPTOR-mTORC1 signaling pathway.
    Article Snippet: .. Prior to treatments, cells were synchronized by serum starvation for 12 h. To establish an in vitro model of renal fibrosis, cells were stimulated with 10 ng/mL of recombinant human TGF-β1 (MedChemExpress, Cat# HY-P7117) for 24 h. For loss-of-function studies, gene silencing was achieved by transfecting cells with 50 nM of either siPREX1 or siRPTOR using Lipofectamine 2000 (Invitrogen). ..

    Inhibition:

    Article Title: Nrf2 overexpression attenuates TGF-β-induced EMT-like changes and ferroptosis-related stress in lung epithelial cells.
    Article Snippet: Objective: Transforming growth factor-β (TGF-β) is a key mediator of epithelial responses associated with pulmonary fibrotic remodeling.. This study examined how nuclear factor erythroid 2-related factor 2 (Nrf2) manipulation affects EMT-like responses and ferroptosis-related stress in TGF-β-treated lung epithelial cells.. Methods: A549 and BEAS-2B cells were treated with TGF-β.

    Concentration Assay:

    Article Title: Nrf2 overexpression attenuates TGF-β-induced EMT-like changes and ferroptosis-related stress in lung epithelial cells.
    Article Snippet: Objective: Transforming growth factor-β (TGF-β) is a key mediator of epithelial responses associated with pulmonary fibrotic remodeling.. This study examined how nuclear factor erythroid 2-related factor 2 (Nrf2) manipulation affects EMT-like responses and ferroptosis-related stress in TGF-β-treated lung epithelial cells.. Methods: A549 and BEAS-2B cells were treated with TGF-β.

    Knockdown:

    Article Title: INHBE is upregulated in MASLD and MASLD-related HCC and promotes lipid accumulation and malignant phenotypes in vitro
    Article Snippet: .. Lipid-loaded Huh7 cells with INHBE knockdown were treated with recombinant human TGF‐β1 (MCE, New Jersey, USA) to pharmacologically activate the SMAD signaling pathway. ..



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